IRAK1 anticorps (pThr387)

N° du produit ABIN1450269

Cet anticorps anti-IRAK1 Polyclonal Lapin (ABIN1450269) détecte spécifiquement IRAK1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IRAK1 anticorps (pThr387) (ABIN1450269)

Antigène: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-IRAK1 anticorps

Épitope: AA 353-402, pThr387

Fonction: IRAK-1 (phospho Thr387) Antibody

Specificité: Phospho-IRAK-1 (T387) Polyclonal Antibody detects endogenous levels of IRAK-1 protein only when phosphorylated at T387.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human IRAK1 around the phosphorylation site of Thr387. AA range:353-402

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur IRAK1

Antigène: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Autre désignation: IRAK1

Sujet:

Synonyms: IRAK1, IRAK, Interleukin-1 receptor-associated kinase 1, IRAK-1

Background: This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: IRAK1

Protein Name: Interleukin-1 receptor-associated kinase 1

Poids moléculaire: 76 kDa

ID gène: 3654

OMIM: 300283

UniProt: P51617

Pathways: Signalisation NF-kappaB, Signalisation TLR, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades