FLIP anticorps (AA 181-230)
Aperçu rapide pour FLIP anticorps (AA 181-230) (ABIN1450919)
Antigène
Voir toutes FLIP (CFLAR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 181-230
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Fonction
- c-FLIP Antibody
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Specificité
- C-FLIP Polyclonal Antibody detects endogenous levels of c-FLIP protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human in ternal CFLAR. AA range:181-230
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
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Autre désignation
- CFLAR
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Sujet
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Synonyms: CFLAR, CASH, CASP8AP1, CLARP, MRIT, CASP8 and FADD-like apoptosis regulator, Caspase homolog, CASH, Caspase-eight-related protein, Casper, Caspase-like apoptosis regulatory protein, CLARP, Cellular FLICE-like inhibitory protein, c-FLIP, FAD
Background: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011],
Gene Name: CFLAR
Protein Name: CASP8 and FADD-like apoptosis regulator
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Poids moléculaire
- 55 kDa
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ID gène
- 8837
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OMIM
- 603599
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UniProt
- O15519
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Pathways
- Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
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