CNGA1 anticorps (AA 401-450)

N° du produit ABIN1451154

Cet anticorps anti-CNGA1 Polyclonal Lapin (ABIN1451154) détecte spécifiquement CNGA1 dans ELISA et WB. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour CNGA1 anticorps (AA 401-450) (ABIN1451154)

Antigène: CNGA1 (Cyclic Nucleotide Gated Channel alpha 1 (CNGA1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNGA1 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-CNGA1 anticorps

Épitope: AA 401-450

Fonction: CNG-1 Antibody

Specificité: CNG-1 Polyclonal Antibody detects endogenous levels of CNG-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human CNGA1. AA range:401-450

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CNGA1

Antigène: CNGA1 (Cyclic Nucleotide Gated Channel alpha 1 (CNGA1))

Autre désignation: CNGA1

Sujet:

Synonyms: CNGA1, CNCG, CNCG1, cGMP-gated cation channel alpha-1, Cyclic nucleotide-gated cation channel 1, Cyclic nucleotide-gated channel alpha-1, CNG channel alpha-1, CNG-1, CNG1, Cyclic nucleotide-gated channel, photoreceptor, Rod photoreceptor cG

Background: The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],

Gene Name: CNGA1

Protein Name: cGMP-gated cation channel alpha-1

Poids moléculaire: 79 kDa

ID gène: 1259

OMIM: 123825

UniProt: P29973

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction, Asymmetric Protein Localization