Insulin Receptor anticorps (pTyr972)
Aperçu rapide pour Insulin Receptor anticorps (pTyr972) (ABIN1495716)
Antigène
Voir toutes Insulin Receptor (INSR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr972
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Specificité
- Human and mouse IR. Rat (100 % homologous) IR has not been tested, but is expected to react. IGF1R [pY950] (75 % homologous) has been shown to cross-react in some cell systems
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Purification
- Immunoaffinity purified
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Immunogène
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Synthetic phosphopeptide derived from the region of the human insulin receptor that contains tyrosine 972, as numbered according to Ebina, et al. (tyrosine 960 according to Ulrich, et al.). The sequence is conserved in mouse and rat.
Type of Immunogen: Synthetic phospho-peptide
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Indications d'application
- Approved: WB (1:1000)
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Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Dulbecco's PBS (without Mg2+, Ca2+), pH 7.3 (+/- 0.1), 50 % glycerol, 1.0 mg/mL BSA (IgG, protease free) as a carrier.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Insulin Receptor (INSR)
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Autre désignation
- Insulin Receptor
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Sujet
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Name/Gene ID: INSR
Subfamily: Insulin receptor
Family: Protein Kinase
Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen -
ID gène
- 3643
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UniProt
- P06213
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Pathways
- Signalisation NF-kappaB, Signalisation RTK, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
Antigène
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