MPZ anticorps
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- Antigène Voir toutes MPZ Anticorps
- MPZ (Myelin Protein Zero (MPZ))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MPZ est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant protein of human MPZ
- Isotype
- IgG
- Top Product
- Discover our top product MPZ Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid freeze / thaw cycles
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- MPZ (Myelin Protein Zero (MPZ))
- Autre désignation
- MPZ (MPZ Produits)
- Synonymes
- anticorps CHM, anticorps CMT1, anticorps CMT1B, anticorps CMT2I, anticorps CMT2J, anticorps CMT4E, anticorps CMTDI3, anticorps CMTDID, anticorps DSS, anticorps HMSNIB, anticorps MPP, anticorps P0, anticorps Mpp, anticorps P-zero, anticorps p0, anticorps sc:d0186, anticorps wu:fc04b11, anticorps wu:fi30g06, anticorps zgc:103775, anticorps myelin protein zero, anticorps myelin protein zero S homeolog, anticorps MPZ, anticorps Mpz, anticorps mpz, anticorps mpz.S
- Sujet
- This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism.,MPZ,CHM,CMT1,CMT1B,CMT2I,CMT2J,CMT4E,CMTDI3,CMTDID,DSS,HMSNIB,MPP,P0,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Neuron marker,Axon marker,MPZ
- Poids moléculaire
- 27 kDa/34 kDa
- ID gène
- 4359
- UniProt
- P25189
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