PKC theta anticorps (pSer695)

N° du produit ABIN1531509

Cet anticorps anti-PKC theta Polyclonal Lapin (ABIN1531509) détecte spécifiquement PKC theta dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PKC theta anticorps (pSer695) (ABIN1531509)

Antigène: PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC theta est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-PKC theta anticorps

Épitope: AA 657-706, pSer695

Fonction: PKC θ (phospho Ser695) Antibody

Specificité: Phospho-PKC θ (S695) Polyclonal Antibody detects endogenous levels of PKC θ protein only when phosphorylated at S695.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human PKC thet around the phosphorylation site of Ser695. AA range:657-706

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur PKC theta

Antigène: PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

Autre désignation: PKC theta

Sujet:

Synonyms: PRKCQ, PRKCT, Protein kinase C theta type, nPKC-theta

Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role.The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008],

Gene Name: PRKCQ

Protein Name: Protein kinase C theta type

Poids moléculaire: 81 kDa

ID gène: 5588

OMIM: 600448

UniProt: Q04759

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling