Lamin A/C anticorps (pSer22)

N° du produit ABIN1532183

Détail du produit anti-Lamin A/C anticorps

Antigène: Lamin A/C (LMNA)

Épitope: AA 2-51, pSer22

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin A/C est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité:

Lamin A (Phospho-Ser22) Antibody detects endogenous levels of Lamin A only when phosphorylated at Ser22.

PhosphorylationH:S22 M:S22 R:S22

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Lamin A around the phosphorylation site of Ser22.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500~1:1000 ELISA: 1:1000

Commentaires:

Unigene-Number: Hs.594444 (NCBI Gene Symbol: LMNA)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable at -20°C for at least 1 year.

Date de péremption: 12 months

Références pour anticorps anti-Lamin A/C (ABIN1532183)

Häge, Sonntag, Svrlanska, Borst, Stilp, Horsch, Müller, Kropff, Milbradt, Stamminger, Schlötzer-Schrehardt, Marschall: "Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation." dans: Viruses, Vol. 13, Issue 2, (2021) (PubMed).

Schütz, Steingruber, Socher, Müller, Wagner, Kögel, Sticht, Marschall: "Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97." dans: Viruses, Vol. 13, Issue 7, (2021) (PubMed).

Häge, Büscher, Pakulska, Hahn, Adrait, Krauter, Borst, Schlötzer-Schrehardt, Couté, Plachter, Marschall: "The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus." dans: Cells, Vol. 10, Issue 11, (2021) (PubMed).

Détails sur Lamin A/C

Antigène: Lamin A/C (LMNA)

Autre désignation: Lamin A (LMNA Produits)

Synonymes: anticorps CDCD1, anticorps CDDC, anticorps CMD1A, anticorps CMT2B1, anticorps EMD2, anticorps FPL, anticorps FPLD, anticorps FPLD2, anticorps HGPS, anticorps IDC, anticorps LDP1, anticorps LFP, anticorps LGMD1B, anticorps LMN1, anticorps LMNC, anticorps LMNL1, anticorps PRO1, anticorps Dhe, anticorps 2459, anticorps 74/76, anticorps CG6944, anticorps D5, anticorps DM[[O]], anticorps Dm, anticorps Dm(0), anticorps Dm0, anticorps Dm1, anticorps Dm2, anticorps DmLamin, anticorps DmO, anticorps Dm[[0]], anticorps Dm[[1]], anticorps Dm[[2]], anticorps Dm[[mit]], anticorps Dm[[o]], anticorps Dmel\\CG6944, anticorps Dmo, anticorps LAM, anticorps Lam Dm[[0]], anticorps Lam(Dm0), anticorps LamDm[[0]], anticorps LamDm[[o]], anticorps Lam[[Dm0]], anticorps Lamin Dm[[0]], anticorps jf27, anticorps l(2)04643, anticorps l(2)25Ec, anticorps l(2)gdh-7, anticorps l(2)gdh7, anticorps l(2)jf27, anticorps lam, anticorps lamDm0, anticorps lamDm[[0]], anticorps lamin, anticorps lamin Dm0, anticorps lamin Dm[[0]], anticorps misg, anticorps nlam, anticorps cb948, anticorps fk66d12, anticorps wu:fk66d12, anticorps lmna-A, anticorps fpl, anticorps idc, anticorps lfp, anticorps cddc, anticorps emd2, anticorps fpld, anticorps hgps, anticorps ldp1, anticorps lmn1, anticorps lmnc, anticorps pro1, anticorps cdcd1, anticorps cmd1a, anticorps cmt2b1, anticorps lgmd1b, anticorps Lamin-A, anticorps lamin-L(III)-like, anticorps lamin A/C, anticorps lamin A, anticorps Lamin, anticorps lamin A/C L homeolog, anticorps lamin-L(III)-like, anticorps LMNA, anticorps Lmna, anticorps Lam, anticorps lmna, anticorps lmna.L, anticorps LMINA

Sujet:

Synonyms: 70 kDa lamin, LAMA, LMN1, LMNA

NCBI Gene Symbol: LMNA

Poids moléculaire: 74 kDa

ID gène: 4000

OMIM: 115200

UniProt: P02545

Pathways: Apoptose, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus