BAX anticorps (AA 41-90)

N° du produit ABIN1532504

Cet anticorps anti-BAX Polyclonal Lapin (ABIN1532504) détecte spécifiquement BAX dans WB, ELISA, IF et ICC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BAX anticorps (AA 41-90) (ABIN1532504)

Antigène: BAX (BCL2-Associated X Protein (BAX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAX est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-BAX anticorps

Épitope: AA 41-90

Fonction: Bax Antibody

Specificité: Bax Polyclonal Antibody detects endogenous levels of Bax protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human BAX. AA range:41-90

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur BAX

Antigène: BAX (BCL2-Associated X Protein (BAX))

Autre désignation: Bax

Sujet:

Synonyms: BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4

Background: RB transcriptional corepressor 1(RB1) Homo sapiens The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],

Gene Name: BAX

Protein Name: Apoptosis regulator BAX

Poids moléculaire: 21 kDa

OMIM: 600040

UniProt: Q07812

Pathways: Signalisation p53, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response