PPARA anticorps (AA 6-55)
Aperçu rapide pour PPARA anticorps (AA 6-55) (ABIN1532643)
Antigène
Voir toutes PPARA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 6-55
-
Fonction
- PPAR-α Antibody
-
Specificité
- PPAR-α Polyclonal Antibody detects endogenous levels of PPAR-α protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Pureté
- > 95 %
-
Immunogène
- The antiserum was produced against synthesized peptide derived from human PPAR-alpha. AA range:6-55
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300. IF 1:50-200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C/1 year
-
Date de péremption
- 12 months
-
-
- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
-
Autre désignation
- PPAR-alpha
-
Sujet
-
Synonyms: PPARA, NR1C1, PPAR, Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1
Background: peroxisome proliferator activated receptor alpha(PPARA) Homo sapiens Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified.This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for thi
Gene Name: PPARA
Protein Name: Peroxisome proliferator-activated receptor alpha
-
Poids moléculaire
- 52 kDa
-
ID gène
- 5465
-
OMIM
- 170998
-
UniProt
- Q07869
-
Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
Antigène
-