MAP2K6 anticorps
Aperçu rapide pour MAP2K6 anticorps (ABIN1532940)
Antigène
Voir toutes MAP2K6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- MEK-6 Antibody
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Specificité
- MEK-6 Polyclonal Antibody detects endogenous levels of MEK-6 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- Synthesized peptide derived from MEK-6 . at AA range: 150-230
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
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Autre désignation
- MKK6
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Sujet
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Synonyms: MAP2K6, MEK6, MKK6, PRKMK6, SKK3, Dual specificity mitogen-activated protein kinase kinase 6, MAP kinase kinase 6, MAPKK 6, MAPK/ERK kinase 6, MEK 6, Stress-activated protein kinase kinase 3, SAPK kinase 3, SAPKK-3, SAPKK3
Background: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008],
Gene Name: MAP2K6
Protein Name: Dual specificity mitogen-activated protein kinase kinase 6
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Poids moléculaire
- 37 kDa
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ID gène
- 5608
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OMIM
- 601254
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UniProt
- P52564
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Pathways
- Signalisation MAPK, Signalisation TLR, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
Antigène
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