AKAP12 anticorps (AA 301-350)

N° du produit ABIN1533824

Cet anticorps anti-AKAP12 Polyclonal Lapin (ABIN1533824) détecte spécifiquement AKAP12 dans IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour AKAP12 anticorps (AA 301-350) (ABIN1533824)

Antigène: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP12 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-AKAP12 anticorps

Épitope: AA 301-350

Fonction: AKAP 250 Antibody

Specificité: AKAP 250 Polyclonal Antibody detects endogenous levels of AKAP 250 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human AKAP12. AA range:301-350

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur AKAP12

Antigène: AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

Autre désignation: AKAP12

Sujet:

Synonyms: AKAP12, AKAP250, A-kinase anchor protein 12, AKAP-12, A-kinase anchor protein 250 kDa, AKAP 250, Gravin, Myasthenia gravis autoantigen

Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell.This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Gene Name: AKAP12

Protein Name: A-kinase anchor protein 12

Poids moléculaire: 191 kDa

ID gène: 9590

OMIM: 604698

UniProt: Q02952

Pathways: cAMP Metabolic Process