RAD51 Homolog B anticorps (AA 201-250)

N° du produit ABIN1534486

L’anticorps anti-RAD51 Homolog B Polyclonal Lapin est utilisé pour la détection de RAD51 Homolog B dans des échantillons de Humain, Souris et Singe. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour RAD51 Homolog B anticorps (AA 201-250) (ABIN1534486)

Antigène: RAD51 Homolog B (Rad51B)

Reactivité: Humain, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51 Homolog B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-RAD51 Homolog B anticorps

Épitope: AA 201-250

Fonction: Rad51B Antibody

Specificité: Rad51B Polyclonal Antibody detects endogenous levels of Rad51B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human RAD51L1. AA range:201-250

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur RAD51 Homolog B

Antigène: RAD51 Homolog B (Rad51B)

Autre désignation: RAD51L1

Sujet:

Synonyms: RAD51B, RAD51L1, REC2, DNA repair protein RAD51 homolog 2, R51H2, RAD51 homolog B, Rad51B, RAD51-like protein 1

Background: RAD51 paralog B(RAD51B) Homo sapiens The protein encoded byThis gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016],

Gene Name: RAD51B

Protein Name: DNA repair protein RAD51 homolog 2

Poids moléculaire: 42 kDa

ID gène: 5890

OMIM: 150699

UniProt: O15315

Pathways: Réparation de l'ADN