Caspase 8 anticorps (Cleaved-Asp384)

N° du produit ABIN1536108

Cet anticorps Lapin Polyclonal détecte spécifiquement Caspase 8 dans WB et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour Caspase 8 anticorps (Cleaved-Asp384) (ABIN1536108)

Antigène: Caspase 8 (CASP8)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 8 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Caspase 8 anticorps

Épitope: AA 335-384, Cleaved-Asp384

Specificité:

Caspase 8 (Cleaved-Asp384) Antibody detects endogenous levels of fragment of activated Caspase 8 resulting from cleavage adjacent to Asp384.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Caspase 8.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500~1:1000 ELISA: 1:40000

Commentaires:

Unigene-Number: Hs.599762 (NCBI Gene Symbol: CASP8)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable at -20°C for at least 1 year.

Date de péremption: 12 months

Références pour anticorps anti-Caspase 8 (ABIN1536108)

Liu, Huang, Liu, Li, Yang, Dou, Liu: "Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation." dans: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 28, Issue 3, pp. 419-25, (2014) (PubMed).

Détails sur Caspase 8

Antigène: Caspase 8 (CASP8)

Autre désignation: Caspase 8

Sujet:

Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog

NCBI Gene Symbol: CASP8

Poids moléculaire: 47 and 55 kDa

ID gène: 841

OMIM: 211980

UniProt: Q14790

Pathways: Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades