This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SPO11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 299-326 amino acids from the C-terminal region of human SPO11.
anticorps CT35, anticorps SPATA43, anticorps TOPVIA, anticorps zgc:77876, anticorps AI449549, anticorps Meiotic recombination protein spo-11, anticorps SPO11, initiator of meiotic double stranded breaks, anticorps SPO11 meiotic protein covalently bound to DSB, anticorps spo-11, anticorps SPO11, anticorps Spo11, anticorps spo11
Sujet
Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.