RASSF1 anticorps (AA 103-132)

N° du produit ABIN1537724

L’anticorps anti-RASSF1 Polyclonal Lapin est utilisé pour la détection de RASSF1 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour RASSF1 anticorps (AA 103-132) (ABIN1537724)

Antigène: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASSF1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB22967

Détail du produit anti-RASSF1 anticorps

Épitope: AA 103-132

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RASSF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the Central region of human RASSF1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: RASSF1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur RASSF1

Antigène: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Autre désignation: RASSF1

Sujet: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Poids moléculaire: 39219

ID gène: 11186

NCBI Accession: NP_001193886, NP_009113, NP_733830, NP_733831, NP_733832

UniProt: Q9NS23