Cet anticorps anti-RASSF1 Monoclonal Souris (Clone 3F3) (ABIN165456) détecte spécifiquement RASSF1 dans WB, ELISA, IF et ICC.
L’anticorps est réactif avec des échantillons de Humain.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing cycles
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Antigène
RASSF1
(Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
Autre désignation
RASSF1A
Sujet
The tumor suppressor gene RASSF1A (3p21.3), human Ras association domain family 1A, is expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, small intestine, colon, and peripheral blood leukocytes. RASSF1A expression is inhibited by hypermethylation of the CpG island including the promoter and early transcribed regions of the human RASSF1A gene. Hypermethylated RASSF1A promoter is observed in primary tumors. Furthermore, RASSF1A is related with cell cycle regulation, apoptosis and microtubule stability.