RASSF1 anticorps (AA 101-340)

N° du produit ABIN3021712

Cet anticorps anti-RASSF1 Polyclonal Lapin (ABIN3021712) détecte spécifiquement RASSF1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour RASSF1 anticorps (AA 101-340) (ABIN3021712)

Antigène: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASSF1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RASSF1 anticorps

Épitope: AA 101-340

Séquence: CCGPRDLGWE PAVERDTNVD EPVEWETPDL SQAEIEQKIK EYNAQINSNL FMSLNKDGSY TGFIKVQLKL VRPVSVPSSK KPPSLQDARR GPGRGTSVRR RTSFYLPKDA VKHLHVLSRT RAREVIEALL RKFLVVDDPR KFALFERAER HGQVYLRKLL DDEQPLRLRL LAGPSDKALS FVLKENDSGE VNWDAFSMPE LHNFLRILQR EEEEHLRQIL QKYSYCRQKI QEALHACPLG

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 101-340 of human RASSF1 (NP_009113.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RASSF1

Antigène: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Autre désignation: RASSF1

Sujet: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.,RASSF1,123F2,NORE2A,RASSF1A,RDA32,REH3P21,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,RASSF1

Poids moléculaire: 8 kDa/9 kDa/16 kDa/21 kDa/31 kDa/38 kDa/39 kDa

ID gène: 11186

UniProt: Q9NS23