DPF1 anticorps (AA 220-247)

N° du produit ABIN1538107

Détail du produit anti-DPF1 anticorps

Antigène: DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))

Épitope: AA 220-247

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPF1 est non-conjugé

Application: Western Blotting (WB)

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DPF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-247 amino acids from the Central region of human DPF1.

Clone: RB37854

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: DPF1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur DPF1

Antigène: DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))

Autre désignation: DPF1 (DPF1 Produits)

Synonymes: anticorps zgc:110104, anticorps DPF1, anticorps req, anticorps xReq, anticorps neud4, anticorps requiem, anticorps neuro-d4, anticorps BAF45b, anticorps NEUD4, anticorps Neud4, anticorps D4, zinc and double PHD fingers family 1, anticorps double PHD fingers 1, anticorps dpf1, anticorps DPF1, anticorps Dpf1

Sujet: DPF1 may have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).

Poids moléculaire: 42502

ID gène: 8193

NCBI Accession: NP_001128627, NP_001128628, NP_004638

UniProt: Q92782