NMDAR2A anticorps (AA 1130-1400)

N° du produit ABIN1681064

Détail du produit anti-NMDAR2A anticorps

Antigène: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Épitope: AA 1130-1400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMDAR2A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: LDPPQFVENV TLPENVDFPD PYQDPSENFR KGDSTLPMNR NPLHNEEGLS NNDQYKLYSK HFTLKDKGSP HSETSERYRQ NSTHCRSCLS NMPTYSGHFT MRSPFKCDAC LRMGNLYDID EDQMLQETGN PATGEQVYQQ DWAQNNALQL QKNKLRISRQ HSYDNIVDKP RELDLSRPSR SISLKDRERL LEGNFYGSLF SVPSSKLSGK KSSLFPQGLE DSKRSKSLLP DHTSDNPFLH SHRDDQRLVI GRCPSDPYKH SLPSQAVNDS Y

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1130-1400 of human NMDAR2A (NP_000824.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NMDAR2A

Antigène: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Autre désignation: GRIN2A (GRIN2A Produits)

Synonymes: anticorps NMDAR2A, anticorps nr2a, anticorps GRIN2A, anticorps EPND, anticorps GluN2A, anticorps NR2A, anticorps glutamate ionotropic receptor NMDA type subunit 2A, anticorps glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog, anticorps glutamate receptor ionotropic, NMDA 2A, anticorps glutamate receptor, ionotropic, NMDA2A (epsilon 1), anticorps GRIN2A, anticorps grin2a.L, anticorps LOC100438553, anticorps Grin2a

Sujet: This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.,EPND,FESD,GluN2A,LKS,NMDAR2A,NR2A,GRIN2A,NMDA 2A,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Dopamine Signaling in Parkinson's Disease,Neurodegenerative Diseases Markers,Other Neurological disorders,Cerebralvascular accident-CVA,GRIN2A

Poids moléculaire: 144 kDa/165 kDa

ID gène: 2903

UniProt: Q12879

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity