MKLN1 anticorps (AA 301-400) (Alexa Fluor 350)

N° du produit ABIN1693093

Détail du produit anti-MKLN1 anticorps (Alexa Fluor 350)

Antigène: MKLN1 (Muskelin 1, Intracellular Mediator Containing Kelch Motifs (MKLN1))

Épitope: AA 301-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MKLN1 est conjugé à/à la Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MKLN1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MKLN1

Antigène: MKLN1 (Muskelin 1, Intracellular Mediator Containing Kelch Motifs (MKLN1))

Autre désignation: MKLN1 (MKLN1 Produits)

Synonymes: anticorps fc60a07, anticorps wu:fc60a07, anticorps mkln1, anticorps MGC81665, anticorps MKLN1, anticorps MGC139211, anticorps TWA2, anticorps A130067F06Rik, anticorps AU015903, anticorps BB154892, anticorps Muskelin, anticorps DKFZp468G1027, anticorps muskelin 1, intracellular mediator containing kelch motifs, anticorps muskelin 1, anticorps muskelin 1 L homeolog, anticorps mkln1, anticorps MKLN1, anticorps mkln1.L, anticorps Mkln1

Sujet:

Synonyms: MKLN 1, Mkln1, MKLN1_HUMAN, muskelin 1, intracellular mediator containing kelch mots, Muskelin.

Background: Muskelin is a 735 amino acid nuclear and cytoplasmic protein that mediates cytoskeletal responses and cell spreading to Thrombospondin 1, an extracellular matrix glycoprotein. Forming a CTLH complex with RMND5A, Ran BP-M and TWA1, Muskelin exists as two alternatively spliced isoforms. Muskelin is implicated as an isoform-specific anchoring protein for the prostaglandin EP3 receptor, and contains one LisH domain, a CTLH domain, six Kelch repeats and an N-terminal discoidin-like domain through which it self-associates via a head-to-tail mechanism. Human and mouse Muskelin share 98 % amino acid seqeuence homology and are encoded by genes located on chromosomes 7q32.3 and 6 A3.3, respectively.