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Thymopoietin anticorps (AA 51-150) (Cy5)

TMPO Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN1704513
  • Antigène Voir toutes Thymopoietin (TMPO) Anticorps
    Thymopoietin (TMPO)
    Épitope
    • 14
    • 13
    • 7
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivité
    • 65
    • 21
    • 16
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 59
    • 6
    Lapin
    Clonalité
    • 60
    • 5
    Polyclonal
    Conjugué
    • 31
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Thymopoietin est conjugé à/à la Cy5
    Application
    • 58
    • 25
    • 19
    • 12
    • 12
    • 12
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Cow
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human LAP2
    Isotype
    IgG
    Top Product
    Discover our top product TMPO Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Thymopoietin (TMPO)
    Abstract
    TMPO Produits
    Synonymes
    anticorps LAP2, anticorps CMD1T, anticorps LEMD4, anticorps PRO0868, anticorps TP, anticorps lap2, anticorps LAP2beta, anticorps 5630400D24Rik, anticorps AI195756, anticorps AI606875, anticorps AW214352, anticorps AW547477, anticorps tmpo, anticorps wu:fc26f12, anticorps wu:fd21f02, anticorps wu:fi29h05, anticorps thymopoietin, anticorps thymopoietin S homeolog, anticorps thymopoietin a, anticorps TMPO, anticorps Tmpo, anticorps tmpo.S, anticorps tmpoa
    Sujet

    Synonyms: Isoforms beta/gamma, Lamina associated polypeptide 2 alpha, Lamina associated polypeptide 2, LAP2, Thymopoietin, Thymopoietin isoform alpha, TMPO, TP alpha, TP, LAP2 alpha, LAP2A_HUMAN.

    Background: The nuclear envelope separates the nucleoplasm from the cytoplasm in eukaryotic cells and includes the outer and inner nuclear membrane, nuclear pore complexes and the nuclear lamina. The nuclear lamina contains intermediate filament-type proteins called lamins that form a dense network to strengthen and stabilize the nuclear envelope. Lamina-associated polypeptide 2 (LAP2) is also known as thymopoietin. LAP2 is a nuclear envelope protein and contains an amino-terminal region called the LAP2-emerin-MAN1 or LEM motif. LAP2 also contains a unique DNA-binding amino-terminal domain. Alternative splicing produces six isoforms (, _,_, and ) of mammalian LAP2 and three isoforms in Xenopus LAP2. LAP2 and LAP2_ associate with chromosomal barrier-to-autointegration factor (BAF) and may play a role in stabilizing chromatin structure. LAP2_ also binds to lamin B. LAP2 is a non-membrane isoform of LAP2 that associates with the internal nucleoskeleton and binds lamin A. The gene encoding human LAP2 maps to chromosome 12q23.1.

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