FGFR3 anticorps (Fibroblast Growth Factor Receptor 3) (pTyr724) (HRP)

Details for Product anti-FGFR3 Antibody No. ABIN1712098, Fournisseur: Connectez-vous pour afficher
Antigène
  • FGFR3
  • LOC100034114
  • ACH
  • CD333
  • CEK2
  • HSFGFR3EX
  • JTK4
  • FR3
  • Fgfr-3
  • Flg-2
  • HBGFR
  • Mfr3
  • sam3
  • fc27h01
  • wu:fc27h01
  • fibroblast growth factor receptor 3
  • fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog
  • FGFR3
  • fgfr3.S
  • Fgfr3
  • fgfr3
Épitope
pTyr724
18
14
14
13
10
10
9
8
6
6
5
4
4
4
3
2
2
2
2
2
2
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
197
51
37
6
4
3
3
1
1
1
1
1
Hôte
Lapin
134
70
1
Clonalité
Polyclonal
Conjugué
Cet anticorp FGFR3 est conjugé à/à la HRP
13
13
9
7
7
5
5
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
138
105
103
59
42
13
12
10
6
6
2
1
1
1
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
Connectez-vous pour afficher
Immunogène KLH conjugated synthetic phosphopeptide derived from human FGFR3 around the phosphorylation site of Tyr724
Isotype IgG
Purification Purified by Protein A.
Autre désignation Fgfr3 (FGFR3 Antibody Extrait)
Sujet

The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.

Synonyms: FGFR3 phospho Y724, FGFR3 phospho Tyr724, p-FGFR3 phospho Y724, ACH, CD 333, CD333, CD333 antigen, CEK 2, CEK2, FGFR 3, Fibroblast growth factor receptor 3 achondroplasia thanatophoric dwarfism, Fibroblast growth factor receptor 3, Heparin binding growth factor receptor, HSFGFR3EX, Hydroxyaryl protein kinase, JTK 4, JTK4, MFR 3, SAM 3, Tyrosine kinase JTK 4, Tyrosine kinase JTK4, Z FGFR 3.

ID gène 2261
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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