GCNT1 anticorps (AA 201-260)

N° du produit ABIN1714546

Détail du produit anti-GCNT1 anticorps

Antigène: GCNT1 (Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1))

Épitope: AA 201-260

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCNT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GCNT1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur GCNT1

Antigène: GCNT1 (Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1))

Autre désignation: GCNT1 (GCNT1 Produits)

Synonymes: anticorps C2GNT, anticorps C2GNT-L, anticorps C2GNT1, anticorps G6NT, anticorps NACGT2, anticorps NAGCT2, anticorps 5630400D21Rik, anticorps B130048E03, anticorps C2 GlcNAcT, anticorps IGnT, anticorps core 2 GlcNAc-T, anticorps glucosaminyl (N-acetyl) transferase 1, core 2 L homeolog, anticorps glucosaminyl (N-acetyl) transferase 1, core 2, anticorps gcnt1.L, anticorps GCNT1, anticorps Gcnt1

Sujet:

Synonyms: 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase, Beta-1, Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, C2GNT, C2GNT L, C2GNT1, C2GnTL, Core 2 branching enzyme, Core 2 GNT, Core 2-branching enzyme, Core2 GlcNAc transferase, Core2-GlcNAc-transferase, GCNT 1, GCNT 1, GCNT1, GCNT1_HUMAN, glucosaminyl N-acetyl transferase 1 core 2, NACGT2.

Background: GCNT1 is expressed in a variety of cell types, including lymphocytes and mucin-producing cells. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectins. Downregulation of Selectin ligand expression levels has been shown to inhibit tissue infiltration. Therefore, GCNT1 represents a potential drug target for the treatment of inflammatory disorders and other pathologies involving Selectins.

ID gène: 2650