DNAJC5 anticorps (AA 1-100)

N° du produit ABIN1715067

Détail du produit anti-DNAJC5 anticorps

Antigène: DNAJC5 (DnaJ (Hsp40) Homolog, Subfamily C, Member 5 (DNAJC5))

Épitope: AA 1-100

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJC5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Réactivité croisée: Humain, Rat

Homologie: Mouse,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CSP

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DNAJC5

Antigène: DNAJC5 (DnaJ (Hsp40) Homolog, Subfamily C, Member 5 (DNAJC5))

Autre désignation: CSP (DNAJC5 Produits)

Synonymes: anticorps CG6395, anticorps CSP, anticorps CSP32, anticorps Cys, anticorps D-CSP, anticorps D.M.CSP, anticorps DCSP-1, anticorps Dcsp, anticorps Dmel\\CG6395, anticorps MAB ab49, anticorps ab49, anticorps anon-WO02059370.50, anticorps csp, anticorps csp29, anticorps csp32, anticorps l(3)03988, anticorps Csp, anticorps GB10835, anticorps cb995, anticorps dnajc5, anticorps zgc:92898, anticorps dnajc5a, anticorps DNAJC5, anticorps CLN4, anticorps CLN4B, anticorps DNAJC5A, anticorps NCL, anticorps 2610314I24Rik, anticorps AU018536, anticorps csp-beta, anticorps Cysteine string protein, anticorps cysteine string protein, anticorps dnaJ homolog subfamily C member 5, anticorps DNAJ/TPR domain-containing protein DNAJC7 family protein, anticorps DnaJ (Hsp40) homolog, subfamily C, member 5aa, anticorps DnaJ heat shock protein family (Hsp40) member C5 gamma L homeolog, anticorps DnaJ heat shock protein family (Hsp40) member C5 gamma, anticorps DnaJ (Hsp40) homolog, subfamily C, member 5, anticorps DnaJ heat shock protein family (Hsp40) member C5, anticorps DnaJ heat shock protein family (Hsp40) member C5 S homeolog, anticorps Csp, anticorps LOC724965, anticorps SJAG_04371, anticorps dnajc5aa, anticorps dnajc5g.L, anticorps Tsp_06120, anticorps dnajc5g, anticorps DNAJC5, anticorps Dnajc5, anticorps dnajc5.S

Sujet:

Synonyms: CLN 4, CLN4, CLN4B, CSP, cysteine string protein alpha, Cysteine string protein, DJC5, DnaJ Hsp40 homolog subfamily C member 5, DnaJ homolog subfamily C member 5, DNAJC 5, Dnajc5, DNAJC5A, DNJC5_HUMAN, NCL.

Background: Cysteine string proteins (CSPs) are synaptic vesicle-associated, secretory vesicle proteins that are involved in Ca2+-regulated exocytosis of synaptic vesicles and modulation of presynaptic transmembrane calcium fluxes in neuroendocrine and endocrine cell types. CSP contains a J-domain that binds HSP 70/HSC 70 chaperone ATPases and a membrane-targeting, palmitoylated cysteine-rich string region. CSPs may act as molecular chaperones in synapses, and mediate conformational folding of components of the vesicular exocytotic machinery. CSP is involved in the fine tuning of neurotransmission through its interaction with receptor-coupled trimeric GTP binding proteins (G proteins) and N-type Ca2+ channels. Two variants of CSP have been described: CSP1, and the 31 amino acid, C-terminally truncated isoform, CSP2. Subcellular fractionation of insulinoma cells shows CSP1 in granular fractions, while the membrane and cytosol fractions contain predominantly CSP2. The fractions also contain additional proteins, presumably CSP dimers. Furthermore, in various mammalian cell lines (including rat brain) CSP1 expression predominates CSP2 expression.

ID gène: 80331

Pathways: Synaptic Vesicle Exocytosis