MAPK10 anticorps (AA 28-233)

N° du produit ABIN1724701

Cet anticorps Souris Monoclonal détecte spécifiquement MAPK10 dans WB, ELISA et ICC. Il présente une réactivité envers Humain et Souris et a été mentionné dans 2+ publications.

Aperçu rapide pour MAPK10 anticorps (AA 28-233) (ABIN1724701)

Antigène: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAPK10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 10E4A4

Détail du produit anti-MAPK10 anticorps

Épitope: AA 28-233

Fonction: MAPK10 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human MAPK10 (aa28-233) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MAPK10 (ABIN1724701)

Tamma, Kalyanaraman, Pahwa, Dominguez, Modesto: "The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells." dans: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 682-8, (2003) (PubMed).

Kinet, Bernard, Mongellaz, Perreau, Goldman, Taylor: "gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes." dans: Blood, Vol. 100, Issue 7, pp. 2546-53, (2002) (PubMed).

Détails sur MAPK10

Antigène: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Autre désignation: MAPK10

Sujet: MAPK10: mitogen-activated protein kinase 10, also known as JNK3, JNK3A, PRKM10, p54bSAPK. Entrez Protein NP_002744. It is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Poids moléculaire: 53 kDa

NCBI Accession: NP_002744

UniProt: P53779

Pathways: Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades