CDC25C anticorps (AA 175-473)

N° du produit ABIN3042352

Détail du produit anti-CDC25C anticorps

Antigène: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Épitope: AA 175-473

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC25C est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for M-phase inducer phosphatase 3(CDC25C) detection. Tested with WB in Human,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for M-phase inducer phosphatase 3(CDC25C) detection. Tested with WB in Human,Rat.
Gene Name: cell division cycle 25C
Protein Name: M-phase inducer phosphatase 3

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Cdc25C recombinant protein (Position: K175-P473). Human Cdc25C shares 78.2% amino acid (aa) sequence identity with mouse Cdc25C.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-CDC25C (ABIN3042352)

Lin, Zhu, Sun, Yang, Sun, Li, Cui, Zheng, Yu: "Prostate cancer cell proliferation is suppressed by microRNA-3160-5p via targeting of F-box and WD repeat domain containing 8." dans: Oncology letters, Vol. 15, Issue 6, pp. 9436-9442, (2018) (PubMed).

Ling, Lu, He, Xiao, Jiang, Su: "Diallyl disulfide selectively causes checkpoint kinase-1 mediated G2/M arrest in human MGC803 gastric cancer cell line." dans: Oncology reports, Vol. 32, Issue 5, pp. 2274-82, (2014) (PubMed).

Détails sur CDC25C

Antigène: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Autre désignation: CDC25C (CDC25C Produits)

Synonymes: anticorps CDC25C, anticorps cdc25, anticorps xcdc25c, anticorps CDC25, anticorps PPP1R60, anticorps Cdc25, anticorps cdc25-3, anticorps xcdc25-3, anticorps cell division cycle 25C, anticorps cell division cycle 25C S homeolog, anticorps CDC25C, anticorps cdc25c, anticorps Cdc25c, anticorps cdc25c.S

Sujet: M-phase inducer phosphatase 3 is an enzyme that in humans is encoded by the CDC25C gene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Synonyms: CDC 25 antibody|Cdc 25C antibody|CDC25 antibody|CDC25C antibody|Cell division cycle 25 homolog C antibody|Cell division cycle 25C antibody|Cell division cycle 25C protein antibody|Dual specificity phosphatase Cdc25C antibody|M phase inducer phosphatase 3 antibody| M-phase inducer phosphatase 3 antibody|Mitosis inducer CDC25 antibody|MPIP3 antibody|MPIP3_HUMAN antibody|Phosphotyrosine phosphatase antibody|PPP1R60 antibody|protein phosphatase 1, regulatory subunit 60 antibody

ID gène: 995

UniProt: P30307

Pathways: Cycle Cellulaire, M Phase