FLIP anticorps (AA 100-251)

N° du produit ABIN1724856

Cité dans 2+ publications. Cet anticorps anti-FLIP est un anticorps Monoclonal produit chez le Souris, détectant FLIP dans ELISA et IHC. Convient pour Humain.

Aperçu rapide pour FLIP anticorps (AA 100-251) (ABIN1724856)

Antigène: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FLIP est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 6G11A6

Détail du produit anti-FLIP anticorps

Épitope: AA 100-251

Fonction: CFLAR Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-FLIP (ABIN1724856)

Rao-Bindal, Rao, Yu, Kleinerman: "Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts." dans: Pediatric blood & cancer, Vol. 60, Issue 4, pp. 575-9, (2013) (PubMed).

Noh, Lee, Sung, Song, Kim, Woo, Kwon, Lee: "CHOP down-regulates cFLIP(L) expression by promoting ubiquitin/proteasome-mediated cFLIP(L) degradation." dans: Journal of cellular biochemistry, Vol. 113, Issue 12, pp. 3692-700, (2012) (PubMed).

Détails sur FLIP

Antigène: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Autre désignation: CFLAR

Sujet: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.

Poids moléculaire: 55.3 kDa

ID gène: 8837

UniProt: O15519

Pathways: Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development