CLEC10A anticorps (Biotin)

N° du produit ABIN181063

Détail du produit anti-CLEC10A anticorps (Biotin)

Antigène: CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CLEC10A est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Specificité: This antibody recognises the CD301 cell surface protein. In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Clone ER-MP23 is reported to block the function of murine CD301. The antibody binds both MGL1 and MGL2 homologues.

Attributs du produit: Synonyms: CLECSF13, CLECSF14, HML, C-type lectin domain family 10 member A, C-type lectinsuperfamily member 14, Macrophage lectin 2

Purification: Affinity Chromatography on Protein G

Immunogène: Balb/c macrophage precursor cell hybrids. Cells from immunised rats were fused with cells of the rat Y3-Ag1. 2. 3 myeloma cell line.

Clone: ER-MP23

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry: Use 10 μL of Neat-1/10 diluted antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Références pour anticorps anti-CLEC10A (Biotin) (ABIN181063)

Lederle, Hartenstein, Meides, Kunzelmann, Werb, Angel, Mueller: "MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma." dans: Carcinogenesis, Vol. 31, Issue 7, pp. 1175-84, (2010) (PubMed).

Détails sur CLEC10A

Antigène: CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))

Autre désignation: CD301 / CLEC10A (CLEC10A Produits)

Synonymes: anticorps CLEC10A, anticorps CD301, anticorps CLECSF13, anticorps CLECSF14, anticorps HML, anticorps HML2, anticorps MGL, anticorps CD301a, anticorps M-ASGP-BP-1, anticorps Mgl, anticorps Mgl1, anticorps Mgll, anticorps C-type lectin domain family 10 member A, anticorps C-type lectin domain containing 10A, anticorps C-type lectin domain family 10, member A, anticorps LOC607405, anticorps CLEC10A, anticorps Clec10a

Sujet: In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated.Synonyms: C-type lectin domain family 10 member A, C-type lectin superfamily member 14, CLECSF13, CLECSF14, HML, Macrophage lectin 2

ID gène: 10462

UniProt: Q8IUN9