ITGB1 anticorps (PE)

N° du produit ABIN181970

L’anticorps Hamster Monoclonal anti-ITGB1 a été validé pour FACS. Il convient pour détecter ITGB1 dans des échantillons de Souris et Rat.

Aperçu rapide pour ITGB1 anticorps (PE) (ABIN181970)

Antigène: ITGB1 (Integrin beta 1 (ITGB1))

Reactivité: Souris, Rat

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGB1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: HM beta 1-1

Détail du produit anti-ITGB1 anticorps (PE)

Specificité: This antibody recognizes the Integrin beta 1 subunit (CD29). Clone HM beta 1.1 is reported to inhibit beta 1 integrin mediated adhesion. (Ref.1) We recommend the use of SM2210LE for this purpose.

Purification: Affinity Chromatography on Protein G.

Immunogène: Purified mouse VLA-4 antigen. Spleen cells from immunised Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry (Neat-1/5): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 0.25 mL distilled water.

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: This product is photosensitive and should be protected from light

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Détails sur ITGB1

Antigène: ITGB1 (Integrin beta 1 (ITGB1))

Autre désignation: CD29 / Integrin beta-1

Sujet: CD29 is a 110KD cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation.Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12

ID gène: 16412

NCBI Accession: NP_034708

UniProt: P09055

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome