CD11b anticorps (PE)
Aperçu rapide pour CD11b anticorps (PE) (ABIN1820250)
Antigène
Voir toutes CD11b (ITGAM) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Clone 5C6 immunoprecipitates a heterodimer of 165 and 95kD. Clone 5C6 also exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. This clone also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.
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Purification
- Ion exchange chromatography
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Immunogène
- Thioglycollate-elicited Peritoneal Macrophages (TPM).
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Isotype
- IgG2b
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Indications d'application
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Approved: Flo (1:10)
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Commentaires
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Target Species of Antibody: Mouse
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Distilled water
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Concentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing. Protect from light.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
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- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Autre désignation
- ITGAM / CD11b
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Sujet
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Name/Gene ID: ITGAM
Family: Integrin
Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain -
ID gène
- 3684
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Pathways
- Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
Antigène
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