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CD11b anticorps (PE)

Cet anticorps anti-CD11b est un anticorps Rat Monoclonal détectant CD11b dans FACS. Adapté pour Humain et Souris.
N° du produit ABIN1820250

Aperçu rapide pour CD11b anticorps (PE) (ABIN1820250)

Antigène

Voir toutes CD11b (ITGAM) Anticorps
CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivité

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Humain, Souris

Hôte

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Rat

Clonalité

  • 356
  • 98
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Monoclonal

Conjugué

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Cet anticorp CD11b est conjugé à/à la PE

Application

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Flow Cytometry (FACS)

Clone

5C6
  • Specificité

    Recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Clone 5C6 immunoprecipitates a heterodimer of 165 and 95kD. Clone 5C6 also exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. This clone also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.

    Purification

    Ion exchange chromatography

    Immunogène

    Thioglycollate-elicited Peritoneal Macrophages (TPM).

    Isotype

    IgG2b
  • Indications d'application

    Approved: Flo (1:10)

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

    Commentaires

    Target Species of Antibody: Mouse

    Restrictions

    For Research Use only
  • Format

    Liquid

    Reconstitution

    Distilled water

    Concentration

    Lot specific

    Buffer

    PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing. Protect from light.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
  • Antigène

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    Autre désignation

    ITGAM / CD11b

    Sujet

    Name/Gene ID: ITGAM
    Family: Integrin

    Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

    ID gène

    3684

    Pathways

    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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