SQSTM1 anticorps (AA 232-356)

N° du produit ABIN1846090

Cet anticorps Souris Monoclonal détecte spécifiquement SQSTM1 dans WB, IHC, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour SQSTM1 anticorps (AA 232-356) (ABIN1846090)

Antigène: SQSTM1 (Sequestosome 1 (SQSTM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SQSTM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Détail du produit anti-SQSTM1 anticorps

Épitope: AA 232-356

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. coli.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Détails sur SQSTM1

Antigène: SQSTM1 (Sequestosome 1 (SQSTM1))

Autre désignation: SQSTM1

Sujet: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway.The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals.Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene.Mutations in this gene result in sporadic and familial Paget disease of bone.

Poids moléculaire: 47.7 kDa

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy