Bcl-2 anticorps (AA 144-171)

N° du produit ABIN1881107

L’anticorps Lapin Polyclonal anti-Bcl-2 a été validé pour WB. Il convient pour détecter Bcl-2 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour Bcl-2 anticorps (AA 144-171) (ABIN1881107)

Antigène: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bcl-2 est non-conjugé

Application: Western Blotting (WB)

Clone: RB41153

Détail du produit anti-Bcl-2 anticorps

Épitope: AA 144-171

Homologie: B, C, Ha, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This BCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-171 amino acids from the Central region of human BCL2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-Bcl-2 (ABIN1881107)

Feng, Stachura, White, Gutierrez, Zhang, Sanda, Jette, Testa, Neuberg, Langenau, Kutok, Zon, Traver, Fleming, Kanki, Look: "T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation." dans: Cancer cell, Vol. 18, Issue 4, pp. 353-66, (2010) (PubMed).

Détails sur Bcl-2

Antigène: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Autre désignation: BCL2

Sujet: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].

Poids moléculaire: 26266

NCBI Accession: NP_000624

UniProt: P10415

Pathways: Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling