CCNDBP1 anticorps (N-Term)

N° du produit ABIN1881181

Détail du produit anti-CCNDBP1 anticorps

Antigène: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Épitope: AA 21-49, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCNDBP1 est non-conjugé

Application: Western Blotting (WB)

Homologie: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CCNDBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of human CCNDBP1.

Clone: RB40537

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CCNDBP1 (ABIN1881181)

Lee, Yeom, Lee, Kang, Park: "A novel senescence-evasion mechanism involving Grap2 and Cyclin D interacting protein inactivation by Ras associated with diabetes in cancer cells under doxorubicin treatment." dans: Cancer research, Vol. 70, Issue 11, pp. 4357-65, (2010) (PubMed).

Seto, Ikushima, Suzuki, Sato, Fukai, Yuki, Miyazawa, Miyazono, Ishitani, Nureki: "Crystallization and preliminary X-ray diffraction analysis of GCIP/HHM transcriptional regulator." dans: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 65, Issue Pt 1, pp. 21-4, (2009) (PubMed).

Ikushima, Komuro, Isogaya, Shinozaki, Hellman, Miyazawa, Miyazono: "An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-beta signalling." dans: The EMBO journal, Vol. 27, Issue 22, pp. 2955-65, (2008) (PubMed).

Chen, Su, Jin, Chang, Chang: "Immunohistochemical expression of GCIP in breast carcinoma: relationship with tumour grade, disease-free survival, mucinous differentiation and response to chemotherapy." dans: Histopathology, Vol. 53, Issue 5, pp. 554-60, (2008) (PubMed).

Chang, Chen, Chen, Su, Chang, Chang: "Ribosomal phosphoprotein P0 interacts with GCIP and overexpression of P0 is associated with cellular proliferation in breast and liver carcinoma cells." dans: Oncogene, Vol. 27, Issue 3, pp. 332-8, (2008) (PubMed).

Détails sur CCNDBP1

Antigène: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Autre désignation: CCNDBP1 (CCNDBP1 Produits)

Synonymes: anticorps CCNDBP1, anticorps dip1, anticorps gcip, anticorps DIP1, anticorps GCIP, anticorps HHM, anticorps AU022347, anticorps Maid, anticorps SECC-8, anticorps SSEC-8, anticorps cyclin D1 binding protein 1, anticorps cyclin D-type binding-protein 1, anticorps CCNDBP1, anticorps ccndbp1, anticorps Ccndbp1

Sujet: This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq].

Poids moléculaire: 40262

NCBI Accession: NP_036274

UniProt: O95273