COL10A1 anticorps (N-Term)

N° du produit ABIN1881220

Détail du produit anti-COL10A1 anticorps

Antigène: COL10A1 (Collagen, Type X, alpha 1 (COL10A1))

Épitope: AA 29-58, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL10A1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This COL10A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human COL10A1.

Clone: RB40406

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-COL10A1 (ABIN1881220)

Mäkitie, Susic, Cole: "Early-onset metaphyseal chondrodysplasia type Schmid associated with a COL10A1 frame-shift mutation and impaired trimerization of wild-type α1(X) protein chains." dans: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 28, Issue 11, pp. 1497-501, (2010) (PubMed).

Wang, Qiu, Ma, Xia, Zhu, Zhu: "Expression of Runx2 and type X collagen in vertebral growth plate of patients with adolescent idiopathic scoliosis." dans: Connective tissue research, Vol. 51, Issue 3, pp. 188-96, (2010) (PubMed).

Videman, Saarela, Kaprio, Näkki, Levälahti, Gill, Peltonen, Battié: "Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing." dans: Arthritis and rheumatism, Vol. 60, Issue 2, pp. 470-81, (2009) (PubMed).

Higashikawa, Saito, Ikeda, Kamekura, Kawamura, Kan, Oshima, Ohba, Ogata, Takeshita, Nakamura, Chung, Kawaguchi: "Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene." dans: Arthritis and rheumatism, Vol. 60, Issue 1, pp. 166-78, (2009) (PubMed).

Zimmermann, Boeuf, Dickhut, Boehmer, Olek, Richter: "Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoter." dans: Arthritis and rheumatism, Vol. 58, Issue 9, pp. 2743-53, (2008) (PubMed).

Détails sur COL10A1

Antigène: COL10A1 (Collagen, Type X, alpha 1 (COL10A1))

Autre désignation: COL10A1 (COL10A1 Produits)

Synonymes: anticorps Col10, anticorps Col10a-1, anticorps collagen, type X, alpha 1, anticorps collagen type X alpha 1 chain, anticorps Col10a1, anticorps COL10A1

Sujet: This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).

Poids moléculaire: 66158

NCBI Accession: NP_000484

UniProt: Q03692