eIF4EBP2 anticorps (C-Term)

N° du produit ABIN1881292

Détail du produit anti-eIF4EBP2 anticorps

Antigène: eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))

Épitope: AA 87-115, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp eIF4EBP2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This EIF4EBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-115 amino acids from the C-terminal region of human EIF4EBP2.

Clone: RB41859

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-eIF4EBP2 (ABIN1881292)

Bidinosti, Martineau, Frank, Sonenberg: "Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain." dans: The Journal of biological chemistry, Vol. 285, Issue 25, pp. 19402-8, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Gingras, Sonenberg: "Adenovirus infection inactivates the translational inhibitors 4E-BP1 and 4E-BP2." dans: Virology, Vol. 237, Issue 1, pp. 182-6, (1997) (PubMed).

Détails sur eIF4EBP2

Antigène: eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))

Autre désignation: EIF4EBP2 (EIF4EBP2 Produits)

Synonymes: anticorps 4ebp2, anticorps MGC75579, anticorps wu:fa55e11, anticorps wu:fp45e09, anticorps MGC78987, anticorps EIF4EBP2, anticorps eIF-4E, anticorps Tb06.28P18.1010, anticorps 4EBP2, anticorps PHASII, anticorps 2810011I19Rik, anticorps 4E-BP2, anticorps AA792569, anticorps BC010348, anticorps PHAS-II, anticorps eukaryotic translation initiation factor 4E binding protein 2, anticorps eukaryotic translation initiation factor 4E binding protein 2 L homeolog, anticorps eukaryotic initiation factor 4E, anticorps eukaryotic translation initiation factor 4E, anticorps putative eukaryotic translation initiation factor 4e, anticorps eif4ebp2, anticorps Eif4ebp2, anticorps eif4ebp2.L, anticorps EIF4EBP2, anticorps eIF-4E, anticorps Tb927.6.1870, anticorps LMJF_30_0450

Sujet: This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.

Poids moléculaire: 12939

NCBI Accession: NP_004087

UniProt: Q13542