FXR1 anticorps (N-Term)

N° du produit ABIN1881357

Détail du produit anti-FXR1 anticorps

Antigène: FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

Épitope: AA 37-66, N-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FXR1 est non-conjugé

Application: Western Blotting (WB)

Homologie: B, Ha, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human FXR1.

Clone: RB41819

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-FXR1 (ABIN1881357)

Coffee, Tessier, Woodruff, Broadie: "Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P." dans: Disease models & mechanisms, Vol. 3, Issue 7-8, pp. 471-85, (2010) (PubMed).

Darnell, Fraser, Mostovetsky, Darnell: "Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs." dans: Human molecular genetics, Vol. 18, Issue 17, pp. 3164-77, (2009) (PubMed).

Purcell, Wray, Stone, Visscher, ODonovan, Sullivan, Sklar: "Common polygenic variation contributes to risk of schizophrenia and bipolar disorder." dans: Nature, Vol. 460, Issue 7256, pp. 748-52, (2009) (PubMed).

Davidovic, Sacconi, Bechara, Delplace, Allegra, Desnuelle, Bardoni: "Alteration of expression of muscle specific isoforms of the fragile X related protein 1 (FXR1P) in facioscapulohumeral muscular dystrophy patients." dans: Journal of medical genetics, Vol. 45, Issue 10, pp. 679-85, (2008) (PubMed).

Vasudevan, Steitz: "AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2." dans: Cell, Vol. 128, Issue 6, pp. 1105-18, (2007) (PubMed).

Détails sur FXR1

Antigène: FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

Autre désignation: FXR1 (FXR1 Produits)

Synonymes: anticorps FXR1P, anticorps wu:fb16f11, anticorps wu:fd18c10, anticorps zgc:66226, anticorps Fxr1h, anticorps Fxr1p, anticorps XtFxr1p, anticorps fxr1h, anticorps xFxr1p, anticorps FXR1, anticorps 1110050J02Rik, anticorps 9530073J07Rik, anticorps AI851072, anticorps xfxr1, anticorps fxr1, anticorps FMR1 autosomal homolog 1, anticorps fragile X mental retardation, autosomal homolog 1, anticorps fragile X mental retardation gene 1, autosomal homolog, anticorps FMR1 autosomal homolog 1 L homeolog, anticorps FMR1 autosomal homolog 1 S homeolog, anticorps FXR1, anticorps fxr1, anticorps Fxr1, anticorps fxr1.L, anticorps fxr1.S

Sujet: The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 69721

NCBI Accession: NP_001013456, NP_001013457, NP_005078

UniProt: P51114