Kv2.2 anticorps (N-Term)

N° du produit ABIN1881474

Détail du produit anti-Kv2.2 anticorps

Antigène: Kv2.2 (KCNB2) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))

Épitope: AA 138-166, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kv2.2 est non-conjugé

Application: Western Blotting (WB)

Homologie: B, M, Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This KCNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the N-terminal region of human KCNB2.

Clone: RB40837

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-Kv2.2 (ABIN1881474)

Cirulli, Kasperaviciūte, Attix, Need, Ge, Gibson, Goldstein: "Common genetic variation and performance on standardized cognitive tests." dans: European journal of human genetics : EJHG, Vol. 18, Issue 7, pp. 815-20, (2010) (PubMed).

Baranzini, Wang, Gibson, Galwey, Naegelin, Barkhof, Radue, Lindberg, Uitdehaag, Johnson, Angelakopoulou, Hall, Richardson, Prinjha, Gass, Geurts, Kragt, Sombekke, Vrenken, Qualley, Lincoln et al.: "Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis...." dans: Human molecular genetics, Vol. 18, Issue 4, pp. 767-78, (2009) (PubMed).

Nyholt, LaForge, Kallela, Alakurtti, Anttila, Färkkilä, Hämaläinen, Kaprio, Kaunisto, Heath, Montgomery, Göbel, Todt, Ferrari, Launer, Frants, Terwindt, de Vries, Verschuren, Brand: "A high-density association screen of 155 ion transport genes for involvement with common migraine." dans: Human molecular genetics, Vol. 17, Issue 21, pp. 3318-31, (2008) (PubMed).

Wu, Ma, Brown, Geisler, Li, Tzeng, Jia, Jurisica, Li: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." dans: Proteomics, Vol. 7, Issue 11, pp. 1775-85, (2007) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." dans: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Détails sur Kv2.2

Antigène: Kv2.2 (KCNB2) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))

Autre désignation: KCNB2 (KCNB2 Produits)

Synonymes: anticorps KCNB2, anticorps si:ch211-193n21.1, anticorps Kv2.2, anticorps 9630047L19Rik, anticorps BB130875, anticorps XShab12, anticorps kcnb2, anticorps KV2.2, anticorps potassium voltage-gated channel subfamily B member 2, anticorps potassium voltage-gated channel, Shab-related subfamily, member 2, anticorps potassium channel, voltage gated Shab related subfamily B, member 2, anticorps potassium voltage gated channel, Shab-related subfamily, member 2, anticorps potassium channel, voltage gated Shab related subfamily B, member 2 S homeolog, anticorps KCNB2, anticorps kcnb2, anticorps LOC100051372, anticorps Kcnb2, anticorps kcnb2.S

Sujet: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel. The gene is expressed in gastrointestinal smooth muscle cells.

Poids moléculaire: 102563

NCBI Accession: NP_004761

UniProt: Q92953