Keratin 86 anticorps (AA 300-327)

N° du produit ABIN1881488

Détail du produit anti-Keratin 86 anticorps

Antigène: Keratin 86 (KRT86)

Épitope: AA 300-327

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Keratin 86 est non-conjugé

Application: Western Blotting (WB)

Homologie: Sh, B, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This KRT86 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-327 amino acids from the Central region of human KRT86.

Clone: RB42669

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-Keratin 86 (ABIN1881488)

ZHANG, MENG, ZHAO, TIAN: "Mutation E402K of the hHb6 in a Chinese Han family with monilethrix." dans: European journal of dermatology : EJD, Vol. 19, Issue 5, pp. 508-9, (2009) (PubMed).

Feng, Liu, Yang: "[Analysis of human hair basic keratin 6 gene mutation in a Chinese Han family with monilethrix]." dans: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, Vol. 25, Issue 2, pp. 141-4, (2008) (PubMed).

Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." dans: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

Schweizer, Bowden, Coulombe, Langbein, Lane, Magin, Maltais, Omary, Parry, Rogers, Wright: "New consensus nomenclature for mammalian keratins." dans: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, (2006) (PubMed).

Détails sur Keratin 86

Antigène: Keratin 86 (KRT86)

Autre désignation: KRT86 (KRT86 Produits)

Synonymes: anticorps Kb26, anticorps KRT86, anticorps HB6, anticorps Hb1, anticorps KRTHB1, anticorps KRTHB6, anticorps MNX, anticorps hHb6, anticorps 5430421N21Rik, anticorps AI325212, anticorps Khb4, anticorps Krt2-10, anticorps Krt2-11, anticorps MHb4, anticorps keratin 86, anticorps hair keratin type II intermediate filament, anticorps Krt86, anticorps KRT86, anticorps KRT2.11

Sujet: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle, this hair keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutations in this gene and KRTHB1 have been observed in patients with a rare dominant hair disease, monilethrix.

Poids moléculaire: 53501

NCBI Accession: NP_002275

UniProt: O43790