PARP3 anticorps (N-Term)

N° du produit ABIN1881632

Détail du produit anti-PARP3 anticorps

Antigène: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Épitope: AA 99-126, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP3 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PARP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-126 amino acids from the N-terminal region of human PARP3.

Clone: RB42819

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur PARP3

Antigène: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Autre désignation: PARP3 (PARP3 Produits)

Synonymes: anticorps ADPRT-3, anticorps PARP-3, anticorps PM38, anticorps Adprtl3, anticorps fj17c06, anticorps wu:fj17c06, anticorps zgc:66157, anticorps PARP3, anticorps parp3, anticorps ADPRT3, anticorps ADPRTL2, anticorps ADPRTL3, anticorps ARTD3, anticorps IRT1, anticorps PADPRT-3, anticorps A930002C11Rik, anticorps AW990611, anticorps Adprt3, anticorps pADPRT-3, anticorps seed maturation protein PM38, anticorps poly (ADP-ribose) polymerase family, member 3, anticorps poly(ADP-ribose) polymerase family member 3, anticorps poly(ADP-ribose) polymerase family member 3 L homeolog, anticorps PARP3, anticorps parp3, anticorps parp3.L, anticorps Parp3

Sujet: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.

Poids moléculaire: 60089

NCBI Accession: NP_001003931, NP_005476

UniProt: Q9Y6F1