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RPS6KA1 anticorps (pThr359)

RPS6KA1 Reactivité: Humain WB, DB Hôte: Lapin Polyclonal RB13385 unconjugated
N° du produit ABIN1881765
  • Antigène Voir toutes RPS6KA1 Anticorps
    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
    Épitope
    • 40
    • 30
    • 25
    • 18
    • 17
    • 16
    • 15
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr359
    Reactivité
    • 207
    • 125
    • 93
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 215
    • 19
    Lapin
    Clonalité
    • 192
    • 43
    Polyclonal
    Conjugué
    • 108
    • 17
    • 14
    • 11
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Cet anticorp RPS6KA1 est non-conjugé
    Application
    • 186
    • 104
    • 54
    • 53
    • 52
    • 27
    • 27
    • 27
    • 15
    • 12
    • 8
    • 3
    • 2
    • 1
    Western Blotting (WB), Dot Blot (DB)
    Homologie
    C, X
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This RPS6KA1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T359 of human RPS6KA1.
    Clone
    RB13385
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RPS6KA1 Anticorps primaire
  • Indications d'application
    WB: 1:2000. DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Roux, Ballif, Anjum, Gygi, Blenis: "Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 37, pp. 13489-94, (2004) (PubMed).

    Bohuslav, Chen, Kwon, Mu, Greene: "p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1." dans: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26115-25, (2004) (PubMed).

    Hu, Fang, Dunham, Prada, Stachowiak, Stachowiak: "90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling." dans: The Journal of biological chemistry, Vol. 279, Issue 28, pp. 29325-35, (2004) (PubMed).

    Fernando, Wimalasena: "Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt." dans: Molecular biology of the cell, Vol. 15, Issue 7, pp. 3266-84, (2004) (PubMed).

  • Antigène
    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
    Autre désignation
    RPS6KA1 (RPS6KA1 Produits)
    Synonymes
    anticorps HU-1, anticorps MAPKAPK1A, anticorps RSK, anticorps RSK1, anticorps Rsk1, anticorps p90rsk, anticorps rsk, anticorps RPS6KA, anticorps hu-1, anticorps mapkapk1a, anticorps rsk1, anticorps wu:fc56h07, anticorps zgc:152654, anticorps ribosomal protein S6 kinase A1, anticorps ribosomal protein S6 kinase polypeptide 1, anticorps ribosomal protein S6 kinase A1-like, anticorps ribosomal protein S6 kinase A1 L homeolog, anticorps ribosomal protein S6 kinase a, polypeptide 1, anticorps RPS6KA1, anticorps Rps6ka1, anticorps RPS6KA1L, anticorps rps6ka1.L, anticorps rps6ka1
    Sujet
    RPS6KA1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation.
    Poids moléculaire
    82723
    NCBI Accession
    NP_001006666, NP_002944
    UniProt
    Q15418
    Pathways
    Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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