SCNN1B anticorps (AA 306-332)

N° du produit ABIN2838920

Détail du produit anti-SCNN1B anticorps

Antigène: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Épitope: AA 306-332

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCNN1B est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SCNN1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-332 amino acids from the Central region of human SCNN1B.

Clone: RB42043

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-SCNN1B (ABIN2838920)

Song, Wei, Zhou, Lazrak, Liu, Londino, Squadrito, Matalon: "Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines." dans: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9716-28, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Azad, Rauh, Vermeulen, Jaspers, Korbmacher, Boissier, Bassinet, Fichou, des Georges, Stanke, De Boeck, Dupont, Balascáková, Hjelte, Lebecque: "Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease." dans: Human mutation, Vol. 30, Issue 7, pp. 1093-103, (2009) (PubMed).

Détails sur SCNN1B

Antigène: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Autre désignation: SCNN1B (SCNN1B Produits)

Synonymes: anticorps BESC1, anticorps ENaCb, anticorps ENaCbeta, anticorps SCNEB, anticorps RNENACB, anticorps besc1, anticorps betaxENaC, anticorps enacb, anticorps enacbeta, anticorps scnn1b, anticorps beta-ENaC, anticorps scneb, anticorps SCNN1B, anticorps BETA-ENAC, anticorps sodium channel epithelial 1 beta subunit, anticorps sodium channel, non voltage gated 1 beta subunit L homeolog, anticorps sodium channel, non voltage gated 1 beta subunit, anticorps sodium channel, nonvoltage-gated 1 beta, anticorps sodium channel, non voltage gated 1 beta subunit S homeolog, anticorps SCNN1B, anticorps Scnn1b, anticorps scnn1b.L, anticorps scnn1b, anticorps scnn1b.S

Sujet: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.

Poids moléculaire: 72659

NCBI Accession: NP_000327

UniProt: P51168