POLG2 anticorps (C-Term)

N° du produit ABIN1882118

Détail du produit anti-POLG2 anticorps

Antigène: POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))

Épitope: AA 348-376, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLG2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This POLG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 348-376 amino acids from the C-terminal region of human POLG2.

Clone: RB17786

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-POLG2 (ABIN1882118)

Haba, Hatakeyama, Kinoshita, Teramae, Azma, Hatano, Matsuda: "The modulation of vascular ATP-sensitive K+ channel function via the phosphatidylinositol 3-kinase-Akt pathway activated by phenylephrine." dans: The Journal of pharmacology and experimental therapeutics, Vol. 334, Issue 2, pp. 673-8, (2010) (PubMed).

Longley, Clark, Yu Wai Man, Hudson, Durham, Taylor, Nightingale, Turnbull, Copeland, Chinnery: "Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia." dans: American journal of human genetics, Vol. 78, Issue 6, pp. 1026-34, (2006) (PubMed).

Détails sur POLG2

Antigène: POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))

Autre désignation: POLG2 (POLG2 Produits)

Synonymes: anticorps POLG2, anticorps im:7158733, anticorps si:ch211-157f15.3, anticorps HP55, anticorps MTPOLB, anticorps PEOA4, anticorps POLB, anticorps POLG-BETA, anticorps POLGB, anticorps mtpolb, anticorps DNA polymerase gamma 2, accessory subunit, anticorps polymerase (DNA directed), gamma 2, accessory subunit, anticorps polymerase (DNA directed), gamma 2, accessory subunit L homeolog, anticorps Polg2, anticorps POLG2, anticorps polg2, anticorps polg2.L

Sujet: The accuracy of mitochondrial DNA (mtDNA) replication depends on the coordinated action of many nuclear-encoded proteins and on the correct balance of nucleotides within the mitochondrial matrix. mtDNA is replicated by DNA polymerase gamma, which is composed of a 140-kD catalytic subunit(POLG1) and a 55-kD accessory subunit (POLG2).

Poids moléculaire: 54911

NCBI Accession: NP_009146

UniProt: Q9UHN1