AIM2 anticorps

N° du produit ABIN1882191

Cet anticorps anti-AIM2 est un anticorps Souris Monoclonal détectant AIM2 dans WB. Adapté pour Humain. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour AIM2 anticorps (ABIN1882191)

Antigène: AIM2 (Absent in Melanoma 2 (AIM2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AIM2 est non-conjugé

Application: Western Blotting (WB)

Clone: 812CT9-2-2-1

Détail du produit anti-AIM2 anticorps

Purification: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogène: This AIM2 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 10-40 region of human AIM2.

Isotype: IgM

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-AIM2 (ABIN1882191)

Chen, Ou-Yang, Hung, Liu, Wang, Wang, Hou, Hortobagyi, Hung: "AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model." dans: Molecular cancer therapeutics, Vol. 5, Issue 1, pp. 1-7, (2006) (PubMed).

Cresswell, Clarke, Jackson, Darcy, Trapani, Johnstone: "Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2." dans: Biochemical and biophysical research communications, Vol. 326, Issue 2, pp. 417-24, (2004) (PubMed).

DeYoung, Ray, Su, Anzick, Johnstone, Trapani, Meltzer, Trent: "Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma." dans: Oncogene, Vol. 15, Issue 4, pp. 453-7, (1997) (PubMed).

Détails sur AIM2

Antigène: AIM2 (Absent in Melanoma 2 (AIM2))

Autre désignation: AIM2

Sujet: Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.

Poids moléculaire: 38954

NCBI Accession: NP_004824

UniProt: O14862

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome