Retinoblastoma Binding Protein 8 anticorps (AA 452-747)

N° du produit ABIN1886481

Cet anticorps anti-Retinoblastoma Binding Protein 8 Polyclonal Lapin (ABIN1886481) détecte spécifiquement Retinoblastoma Binding Protein 8 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Retinoblastoma Binding Protein 8 anticorps (AA 452-747) (ABIN1886481)

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoblastoma Binding Protein 8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Retinoblastoma Binding Protein 8 anticorps

Épitope: AA 452-747

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 452 and 747 of CtIP

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur Retinoblastoma Binding Protein 8

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Autre désignation: CtIP

Sujet: The protein encoded by this gene is a ubiquitously expressed nuclear protein.It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation.This protein complexes with transcriptional co-repressor CTBP.It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control.It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1.Three transcript variants encoding two different isoforms have been found for this gene.More transcript variants exist, but their full-length natures have not been determined.[provided by RefSeq]

Poids moléculaire: 102 kDa

ID gène: 5932

NCBI Accession: NM_002894, NP_002885

Pathways: Cycle Cellulaire, Réparation de l'ADN