TYK2 anticorps (AA 680-1176)

N° du produit ABIN1886613

Cet anticorps anti-TYK2 est un anticorps Lapin Polyclonal détectant TYK2 dans WB et IF. Adapté pour Humain.

Aperçu rapide pour TYK2 anticorps (AA 680-1176) (ABIN1886613)

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TYK2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-TYK2 anticorps

Épitope: AA 680-1176

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 680 and 1176 of TYK2

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur TYK2

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Autre désignation: TYK2

Sujet: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families.This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits.It is also component of both the type I and type III interferon signaling pathways.As such, it may play a role in anti-viral immunity.A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.[provided by RefSeq]

Poids moléculaire: 134 kDa

ID gène: 7297

NCBI Accession: NM_003331, NP_003322

Pathways: Signalistation JAK/STAT, Hepatitis C