VAV1 anticorps (AA 83-538)

N° du produit ABIN1886679

Cet anticorps anti-VAV1 est un anticorps Lapin Polyclonal détectant VAV1 dans WB et IHC. Adapté pour Humain.

Aperçu rapide pour VAV1 anticorps (AA 83-538) (ABIN1886679)

Antigène: VAV1 (Vav 1 Oncogene (VAV1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VAV1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-VAV1 anticorps

Épitope: AA 83-538

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 83 and 538 of Human VAV1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur VAV1

Antigène: VAV1 (Vav 1 Oncogene (VAV1))

Autre désignation: VAV1

Sujet: The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins.The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation.This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1.Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.[provided by RefSeq]
Synonyms: VAV

Poids moléculaire: 98 kDa

ID gène: 7409

NCBI Accession: NM_005428, NP_005419

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling