SYPL2 anticorps (C-Term)

N° du produit ABIN1887064

Détail du produit anti-SYPL2 anticorps

Antigène: SYPL2 (Synaptophysin-Like 2 (SYPL2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYPL2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée (Details): At least two isoforms of SYPL2 are known to exist. SYPL2 antibody will not cross-react with SYPL1.

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the carboxy terminus of human SYPL.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur SYPL2

Antigène: SYPL2 (Synaptophysin-Like 2 (SYPL2))

Autre désignation: SYPL2 (SYPL2 Produits)

Synonymes: anticorps AI552439, anticorps Mg29, anticorps MG29, anticorps mg29, anticorps MGC88982, anticorps Sypl, anticorps fc22a07, anticorps wu:fc22a07, anticorps zgc:110355, anticorps sypl, anticorps wu:fd54d09, anticorps zgc:65838, anticorps synaptophysin-like 2, anticorps synaptophysin like 2, anticorps synaptophysin like 2 S homeolog, anticorps synaptophysin-like 2b, anticorps synaptophysin-like 2a, anticorps Sypl2, anticorps SYPL2, anticorps sypl2.S, anticorps sypl2, anticorps sypl2b, anticorps sypl2a

Sujet: SYPL2, also known as Mitsugumin 29, was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family.SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle.SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR), thereby influencing intracellular Ca2+ homeostasis through changes in the RyR/Ca2+ release function.Co-expression of SYPL2 and RyR in cultured cells leads to apoptotic cell death resulting from the depletion of Ca2+ from the intracellular stores.
Synonyms: SYPL2, Synaptophysin-like protein 2, mitsugumin 29, MG29

NCBI Accession: NP_001035799