ANKRD27 anticorps (Center)

N° du produit ABIN1887571

Détail du produit anti-ANKRD27 anticorps

Antigène: ANKRD27 (Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKRD27 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the center of human VARP.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur ANKRD27

Antigène: ANKRD27 (Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27))

Autre désignation: VARP (ANKRD27 Produits)

Synonymes: anticorps VARP, anticorps AA408090, anticorps BC016493, anticorps D330003H11Rik, anticorps Varp, anticorps ankyrin repeat domain 27, anticorps ankyrin repeat domain 27 (VPS9 domain), anticorps ANKRD27, anticorps Ankrd27

Sujet: The VPS9 ankyrin repeat protein (VARP) binds to the Rab21, a guanine nucleotide exchange factor that plays an essential role in endocytic trafficking.VARP localizes to early endosomes and is thought to regulate endosome dynamics.VARP also interacts with TI-VAMP/VAMP7, a vesicular SNARE that mediates an exocytic pathway that is crucial to neurite growth.Depletion of VARP by RNA interference impairs neurite growth, suggesting that VARP is a positive regulator of neurite growth.
Synonyms: VPS9 ankyrin repeat protein, Ankyrin repeat domain-containing protein 27, ANKRD27, PP12899

NCBI Accession: NP_115515