TRIM30 anticorps (N-Term)

N° du produit ABIN1888144

Détail du produit anti-TRIM30 anticorps

Antigène: TRIM30 (Trim30) (Tripartite Motif Containing 30 (Trim30))

Épitope: N-Term

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM30 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 24 amino acid peptide near the amino terminus of the mouse TRIM30.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur TRIM30

Antigène: TRIM30 (Trim30) (Tripartite Motif Containing 30 (Trim30))

Autre désignation: TRIM30 (Trim30 Produits)

Synonymes: anticorps RGD1563970, anticorps Rpt-1, anticorps Rpt1, anticorps Trim30, anticorps tripartite motif-containing 30, anticorps tripartite motif-containing 30A, anticorps Trim30, anticorps Trim30a

Sujet: TRIM30 belongs to a family of the tripartite motif (TRIM) proteins involved in the regulation of cell proliferation, differentiation, development, oncogenesis, apoptosis and antiviral responses.The TRIM protein family is an expanding family of RING ('really interesting new gene') proteins, also known as RBCC proteins as they contain an RBCC motif, which comprises a RING domain, one or two B-boxes and a predicted coiled-coil region.Studies have shown that some TRIM family members are critical to innate immunity, TRIM5, TRIM19 and TRIM25, for example, have been shown to restrict viral infection.A recent study shows that TRIM30 functions as a negative modulator of the TLR signaling pathway, by targeting TAB2 and TAB3, and contributes to the inhibition of TLR-mediated NF-kappaB activation.The importance of TRIM30 in the attenuation or termination of NF-kappaB activation suggests that targeting of TAB2 and TAB3 by TRIM30alpha may be a mechanism for modulating many types of immune responses.
Synonyms: Tripartite motif-containing 30, Rpt-1, Rpt1, down regulatory protein of interleukin 2 receptor

NCBI Accession: NP_033125