CCL20 anticorps (PE)

N° du produit ABIN192398

L’anticorps Souris Monoclonal anti-CCL20 a été validé pour FACS. Il convient pour détecter CCL20 dans des échantillons de Humain. Il y a 6+ publications disponibles.

Aperçu rapide pour CCL20 anticorps (PE) (ABIN192398)

Antigène: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCL20 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: UCHL1

Détail du produit anti-CCL20 anticorps (PE)

Fonction: Anti-Hu CD45R0 PE

Specificité: The antibody UCHL1 recognizes an extracellular epitope of CD45R0, a 180 kDa low molecular weight isoform of the leukocyte common antigen (LCA). The antigen is expressed on a subset of memory/activated T cells and on cortical thymocytes.

Réactivité croisée (Details): Human

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Human IL-2 dependent T cells

Isotype: IgG2a

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Reconstitution: No reconstitution is necessary.

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.
Avoid prolonged exposure to light.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Références pour anticorps anti-CCL20 (PE) (ABIN192398)

Akbar, Terry, Timms, Beverley, Janossy: "Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 140, Issue 7, pp. 2171-8, (1988) (PubMed).

Beverley, Merkenschlager, Terry: "Phenotypic diversity of the CD45 antigen and its relationship to function." dans: Immunology. Supplement, Vol. 1, pp. 3-5, (1988) (PubMed).

Terry, Brown, Beverley: "The monoclonal antibody, UCHL1, recognizes a 180,000 MW component of the human leucocyte-common antigen, CD45." dans: Immunology, Vol. 64, Issue 2, pp. 331-6, (1988) (PubMed).

Beverley: "Human T cell subsets." dans: Immunology letters, Vol. 14, Issue 4, pp. 263-7, (1987) (PubMed).

Norton, Ramsay, Smith, Beverley, Isaacson: "Monoclonal antibody (UCHL1) that recognises normal and neoplastic T cells in routinely fixed tissues." dans: Journal of clinical pathology, Vol. 39, Issue 4, pp. 399-405, (1986) (PubMed).

Smith, Brown, Rowe, Callard, Beverley: "Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1." dans: Immunology, Vol. 58, Issue 1, pp. 63-70, (1986) (PubMed).

Détails sur CCL20

Antigène: CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))

Autre désignation: CD45R0

Sujet: CD45R0 is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45R0 is expressed e.g. on macrophages, CD8+ T cells, activated T cells and myeloma cells.,PTPRCR, T200R0

Pathways: Phosphorylation & l'infection par le SRAS-CoV-2